Cinnamic acids and derivatives
Medchemexpress LLC Tyrphostin 8 | 3785-90-8 | 98.0% | 170.17 g/mol | C10H6N2O | 5 MG
Tyrphostin 8 is a small-molecule tyrosine kinase inhibitor supplied for research use. It inhibits EGFR kinase (IC50 = 560 μM), acts as a GTPase inhibitor, and inhibits calcineurin (IC50 = 21 μM). The compound is provided as a high-purity solid and is available in small-mass vials or as a DMSO solution for in vitro biochemical and cell-based assays.
- High purity (>98%), suitable for in vitro studies.
- Known activity against EGFR, GTPase, and calcineurin targets.
- Molecular weight 170.17 g/mol and formula C10H6N2O.
- Available in multiple small pack sizes and as a 10 mM DMSO solution.
- Light yellow to yellow solid for handling and storage.
TARGETMOL CHEMICALS INC E/Z-DEMETHOXYCURCUMIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (p-Hydroxycinnamoyl)feruloylmethane is found in Curcuma zedoaria and Etlingera elatior. It has a role as a metabolite an antineoplastic agent and an anti-inflammatory agent. purity: 98%
Medchemexpress LLC Entacapone | 130929-57-6 | MFCD00866580 | 99.2% | C14H15N3O5 | 10MG
Entacapone (Standard) is an analytical reference standard of entacapone (CAS 130929-57-6) supplied for research and analytical applications. It is intended for use in qualitative and quantitative assays, method development, and validation for chromatographic and mass spectrometric techniques.
- Provides a certified analytical standard for assay development and method validation.
- High purity reference material (≈99.2%).
- Suitable for HPLC, GC, and MS applications.
- Light yellow solid, stable under recommended storage conditions.
- Supports studies of catechol-O-methyltransferase activity and Parkinson's disease research.
Apexbio Technology LLC Tyrphostin AG 1296 146535-11-7 10mM (in 1mL DMSO)
Tyrphostin AG 1296 (CAS 146535-11-7) is a selective inhibitor of platelet-derived growth factor receptor (PDGFR) kinase via ATP-competitive binding Its inhibitory activity (IC50 0 3 0 5 M) results from inducing conformational changes in the ATP-binding domain of PDGFR blocking receptor autophosphorylation induced by ligand binding In vitro studies demonstrate inhibition of PDGF-stimulated mitogenesis (IC50 1 5 M) and cell proliferation (IC50 3 2 M) using Swiss 3T3 cells without significant effects on EGF receptor signaling at concentrations up to 100 M Tyrphostin AG 1296 serves as a research tool for investigating PDGFR-mediated signaling pathways
Medchemexpress LLC Tyrphostin 8 | 3785-90-8 | MFCD00020189 | 98.0% | 170.17 g/mol | C10H6N2O | 10 MG
Tyrphostin 8 is a small-molecule tyrosine kinase inhibitor used as a research reagent to investigate EGFR signaling and related pathways. The compound is supplied as a light yellow to yellow solid with high reported purity and is offered in multiple solid sizes and DMSO solution formats.
- Inhibits EGFR kinase; reported IC50 ≈ 560 μM
- Also exhibits GTPase inhibitory activity
- High purity for reproducible experimental results
- Available as solid and as 10 mM DMSO solution in multiple sizes
- Storage recommended: solid at 4°C under nitrogen; solutions at -80°C or -20°C
Sigma Aldrich Fine Chemicals Biosciences Rivaroxaban R enantiomer U20MG
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Medchemexpress LLC SAR405 R enantiomer | 1946010-79-2 | 99.9% | 443.85 | C19H21ClF3N5O2 | 10MG
SAR405 R enantiomer is the less active stereoisomer of the PIK3C3/Vps34 inhibitor SAR405, provided as a solid for in vitro research use only. It is suited for comparative pharmacology and control studies and includes handling and storage guidance for reliable experimental use.
- Less active enantiomer used as a comparative control in assays.
- High purity (≈99.9%).
- Solid, white to off-white appearance.
- Molecular formula C19H21ClF3N5O2; molecular weight 443.85.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Store powder at -20°C for long-term stability; store solutions at -80°C.
- Intended for laboratory research use only.
Medchemexpress LLC Tyrphostin A9 | 10537-47-0 | MFCD00209853 | 99.9% | 282.38 g/mol | C18H22N2O | 10 MG
Tyrphostin A9 is a small-molecule PDGFR inhibitor provided as an analytical standard for research applications. It is used in biochemical and cell-based studies to investigate tyrosine kinase signaling and mitochondrial dynamics. The material is supplied with purity and storage information and is available in multiple solid and solution formats for laboratory use.
- High purity suitable for analytical and research use.
- Useful as a PDGFR and tyrosine kinase inhibitor in cell and biochemical assays.
- Available in solid and solution formats for flexible experimental workflows.
- Documented stability when stored under recommended conditions.
- Supplied with supporting documentation such as a certificate of analysis or data sheet.
Apexbio Technology LLC E-CINNAMAMIDE-1G
(E)-Cinnamamide (CAS No 22031-64-7) is a synthetic organic compound frequently used in biomedical research It originates from the naturally occurring cinnamic acid and is studied for its potential biological activities The compound acts through various molecular pathways and has been shown to interact with cellular targets impacting inflammatory and cancer pathways Commonly its in vitro activity is observed in the nanomolar to low micromolar range (E)-Cinnamamide is used in various research applications including drug screening assays cancer cell line studies and animal models to evaluate its therapeutic potential Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC AEGELINE-500MG
Aegeline (CAS No 456-12-2) is a bioactive compound under investigation in the field of biomedical research originating from the leaves of the Aegle marmelos tree It primarily acts through modulation of the adrenergic receptor pathways influencing metabolic and cardiovascular processes In vitro studies show its activity in the nanomolar to low micromolar range highlighting its potential in affecting cellular metabolism and energy regulation Researchers commonly employ aegeline in various experimental models including cellular assays and animal studies to explore its pharmacological effects and therapeutic potential It is often used in drug screening programs to evaluate its efficacy and safety profiles Experimental concentrations typically depend on the specific research design allowing for tailored investigation into its mechanisms and applications across diverse biological systems